Prof. Dr. Gyula Batta

Dr. Gyula Batta professor

Department name University of Debrecen, Faculty of Science and Technology, Institute of Chemistry, Department of Organic Chemistry
Central phone number +36 52 512 900 / 22234
E-mail
Address 4032 Debrecen, Egyetem tér 1.
Building, floor, room number Chemistry building, lower ground, lower ground floor, E-18 (study room)
WebsiteTudóstér profile

http://www.structbiol.unideb.hu/

Citizenship: Hungarian

Degrees:

  • Distinguished Professor, University of Debrecen, Chemistry (2006)
  • Dr. habil. (habilitation), University of Debrecen, Chemistry (2002)
  • Doctor of the Hungarian Academy of Sciences (D.Sc.)
  • Chemistry (2001)
  • Candidate degree / Doctor of Philosophy (Ph.D.)
  • Chemistry
  • Hungarian Academy of Sciences, Budapest, Hungary (1988)
  • University Doctor (Univ.Dr.)
  • Chemistry
  • Lajos Kossuth University, Debrecen, Hungary (1984)
  • Master of Science (M.Sc.)
  • Physics
  • Lajos Kossuth University, Debrecen, Hungary (1976)

Professional Appointments:

  • Present appointment:
  • Professor of Chemistry
  • Department of Organic Chemistry, University of Debrecen, Hungary (2009-)

Past appointments:

  • Professor of Chemistry
    • Department of Biochemistry, University of Debrecen, Hungary (2007-2009)
  • Senior Research Scientist
    • Research Group for Antibiotics of the HAS, University of Debrecen, Hungary (1988-2006)
  • Research Associate
    • Department of Organic Chemistry, Lajos Kossuth University, Debrecen, Hungary (1980-1988)
  • Research Engineer
    • Medicor Works, Debrecen, Hungary (1976-1980)
  • Postdoctoral Fellow (STINT fellowship)
    • Arrhenius Laboratory, Stockholm University, Stockholm (2000) Advisor: Prof. Jozef Kowalewski
  • Postdoctoral Fellow
    • Department of Chemistry, University of Arizona, Tucson, Arizona, USA (1993 -1994) Advisor: Prof. Jacquelyne Gervay
  • Postdoctoral Fellow (Go west fellowship)
    • Department of Chemistry, University of Cambridge, UK (1994) Advisor: Prof. Dudley H. Williams
  • Postdoctoral Fellow
    • Department of Chemistry, Royal Insitute of Technology, Stockholm (1992) Advisor: Prof. Julius Glaser

Awards and Honors:

  • Erdey László Award from the Hungarian Academy of Sciences (1987) Achievement: for analytical chemistry research of young scientists
  • Széchenyi Professorship from the Ministry of Education, Hungary (1998-2001) Achievement: NMR spectroscopy research
  • Szentágothai János fellowship of national excellence (2013-2014) Achievement: Structure-function aspects of antifungal disulfide miniproteins
  • Hungarian Cross of Merit by: President of Hungary (2019)
  • Achievement: Structure and mode of action studies of new antimicrobial agents

Memberships in professional societies:

  • Hungarian Chemical Society (Hungarian Academy of Sciences, HAS)
  • Hungarian Society for Microbiology
  • National Committee of NMR Spectroscopy (Hungarian Academy of Sciences)
  • ISMAR (International Society of Magnetic Resonance)
  • Working Committee of Research for Antibiotics (Hungarian Academy of Sciences)
  • Working Committee of Research for Carbohydrates (Hungarian Academy of Sciences)
  • Organizer of the CHI90 International NMR Workshop (Balatonszemes, 1990) and the Central European NMR Symposium and Bruker Users Meeting (Debrecen, 2006).
  • The Open Glycoscience Journal, Bentham Science Publishers, member of the Editorial Board (2009-)
  • COST Action MP0802, Self-assembled guanosine structures for molecular electronic devices Member of the Management Committee, g4net.org, (2008-2012)
  • Organizer of the MP0802 MC meeting and conference in Debrecen (2009)
  • Contributor to the EAST-NMR Research Infrastructure project (FP7) (2009-2013)
  • Member of the Organic and Biomolecular Chemistry Committee of the HAS (2011-)
  • Organizing committee member of MMCE2017 conference, http://mmce2017.hu/ e
  • President, Hungarian NMR Working Committee of HAS and Hungarian Chemical Society (2018-)

Editorial board member:

  • The Journal of Antibiotics https://www.nature.com/ja/ International Journal of Molecular Sciences, Macromolecules  http://www.mdpi.com/journal/ijms
  • Ad hoc reviewer for the following journals and organizations: Journal of Basic Microbiology
  • European Journal of Medicinal Chemistry Chemical Biology and Drug Design Journal of the American Chemical Society Journal of Organic Chemistry
  • FEBS Letters Carbohydrate Research
  • Magnetic Resonance in Chemistry Journal of Magnetic Resonance Concepts in Magnetic Resonance

Research funding organizations:

  • Hungarian Scientific Research Fund (OTKA)
  • Marie-Curie fellowship
  • ESF proposal for Physical and Engineering Sciences
  • Transnational Access to EU-NMR Research Infrastructures
  • TÉT, Hungarian fund for bilateral co-operations

Recent research support:

  • Hungarian Scientific Research Fund (OTKA-ANN 110821, PI) Structure and Function of the Antifungal Proteins PAFB and NFAP.
  • (2014-2017)
  • Hungarian Scientific Research Fund (NKFI-K 119494, participant) Computational, synthetic and analytical investigation of the self-assembly of guanine analogues ( 2018-2021)
  • Hungarian Scientific Research Fund (NKFI-123932, participant) Synthesis and antibacterial evaluation of semisynthetic glycopeptides and multivalent carbohydrates. (2016-2020)
  • EU Regional Development Fund, GINOP-2.3.2-15-2016-00008, DECHEM, workgroup leader, Antimicrobial proteins and glycopeptides (2016-2020)

Publication activity:

  • Peer reviewed publications: 220
  • Number of citations / fully independent: 3898 / 2631 (MTMT2) h-index: 31
  • Researcher ID: H-4567-2011 ORCID: 0000-0002-0442-1828

Selected papers:
 
1.    Váradi Györgyi, Tóth Gábor, Batta Gyula, Structure and Synthesis of Antifungal Disulfide β-Strand Proteins from Filamentous Fungi, Microorganisms 7 : 1 Paper: 5 , 10 p. (2019)

2.    Anna Huber, Dorottya Hajdu, Doris Bratschun-Khan, Zoltán Gáspári, Mihayl Varbanov, Stéphanie Philippot, Ádám Fizil, András Czajlik, Zoltán Kele, Christoph Sonderegger, László Galgóczy, Andrea Bodor, Florentine Marx, Gyula Batta, New antimicrobial potential and structural properties of PAFB: a cationic, cysteine-rich protein from Penicillium chrysogenum Q176, SCIENTIFIC REPORTS 8 Paper: 1751 , 16 p. (2018)

3.    Batta, Gyula ; Bodor, Andrea ; Kövér, Katalin ; Martinek, Tamás ; Perczel, András ; Tőke, Orsolya, NMR- és ESR-spektroszkópia, In: Buday, L; Nyitray, L; Perczel, A (szerk.) Ezerarcú fehérjék, Budapest, Magyarország : Semmelweis Kiadó és Multimédia Stúdió, (2018) pp. 203-256. , 54 p.

4.    Dorottya Hajdu, Anna Huber, András Czajlik, Liliána Tóth, Zoltán Kele, Sándor Kocsubé, Ádám Fizil, Florentine Marx, László Galgóczy, Gyula Batta, Solution structure and novel insights into phylogeny and mode of action of the Neosartorya (Aspergillus) fischeri antifungal protein (NFAP) International Journal of Biological Macromolecules, 2019/2/7

5.    Fizil, Ádám ; Sonderegger, Christoph ; Czajlik, András ; Fekete, Attila ; Komáromi, István
; Hajdu, Dorottya ; Marx, Florentine ; Batta, Gyula, Calcium binding of the antifungal protein PAF: Structure, dynamics and function aspects by NMR and MD simulations, PLOS ONE 13
: 10 Paper: e0204825 , 19 p. (2018)

6.    Christoph Sonderegger, Ádám Fizil, Laura Burtscher, Dorottya Hajdu, Alberto Muńoz, Zoltán Gáspári, Nick D Read, Gyula Batta, Florentine Marx: D19S mutation of the cationic, cysteine-rich protein PAF: novel insights into its structural dynamics, thermal unfolding and antifungal function PLOS ONE 12:(1) Paper e0169920. 21 p. (2017)

7.    Sándor Boros, Gyula Batta: Offset-compensated and zero-quantum suppressed ROESY provides accurate 1H–1H distances in small to medium-sized molecules, MAGNETIC RESONANCE IN CHEMISTRY 54:(12) pp. 947-952. (2016)

8.    Fizil Á, Gáspári Z, Barna T, Marx F, Batta G: "Invisible" Conformers of an Antifungal Disulfide Protein Revealed by Constrained Cold and Heat Unfolding, CEST-NMR Experiments, and Molecular Dynamics Calculations.CHEMISTRY-A EUROPEAN JOURNAL 21:(13) pp. 5136-5144. (2015)

9.    Spadaccini R, Ercole C, Gentile MA, Sanfelice D, Boelens R, Wechselberger R, Batta G, Bernini A, Niccolai N, Picone D: NMR Studies on Structure and Dynamics of the Monomeric Derivative of BS-RNase: New Insights for 3D Domain Swapping, PLOS ONE 7:(1) Paper e29076. 11 p. (2012)

10.    Gyula Batta, Teréz Barna, Zoltán Gáspári, Szabolcs Sándor, Katalin E Kövér, Ulrike Binder, Bettina Sarg, Lydia Kaiserer, Anil Kumar Chhillar, Andrea Eigentler, Éva Leiter, Nikoletta Hegedüs, István Pócsi, Herbert Lindner, Florentine Marx: Functional Aspects of the Solution Structure and Dynamics of PAF, a Highly Stable Antifungal Protein from Penicillium chrysogenum, FEBS JOURNAL 276:(10) pp. 2875-2890. (2009)

Updated: 2021.02.09.


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