Röntgendiffrakciós Szerkezetvizsgáló Laboratórium
The Laboratory for X-ray Diffraction was established in 1996 and headed by Attila Bényei. Structure determination of small molecules was started in 1997 using a Bruker-Nonius MACH3 four circle single crystal diffractometer. The Grant No. GINOP-2.3.3-15-2016-00004 made it possible to install a modern in house diffractometer system in December, 2017. Our instrumentation consists of a Bruker D8 Venture diffractometer with dual IμS 3.0 microsource with Cu Kα radiation for proteins and organic molecules and Mo Kα for metal complexes. The detector is a Charge Integrating Pixel Array Detector (Photon II) and the system is complete with Oxford Cryosystem Cryostream 800+ cooler for 80-500 K measurements as well as the necessary software resources.
Our research is supported by the EU and co-financed by the European Regional Development Fund under the projects GINOP-2.3.2-15-2016-00008 and GINOP-2.3.3-15-2016-00004.
The main co-operating partners are Universities and academic research groups in Hungary and worldwide (USA, Scotland, Spain, South Africa) and pharmaceutical companies.
Our main research fields include single crystal growing; solid state structure by single crystal X-ray diffraction, determination of absolute configuration; ab initio structure determination from powder diffraction data; polymorph screening, ATR-IR/XRPD study of polymorphs, comparison of polymorph structures, analysis of hydrogen bond patterns; testing and measuring protein crystals to obtain beam line time at synchrotrons.